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Department: | 06 - Process & Analytical Sciences |
Location: | Waltham, MA |
Position Summary:
TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are looking for an experienced Scientist or Process Engineer to join our Manufacturing Science team, supporting TScan’s cell therapy manufacturing process development and GMP production of clinical cell therapy candidates. The ideal candidate should have relevant experience in cell therapy process development, technology transfer to GMP manufacturing and GMP principles related to cell therapy, and enjoy fast-paced, collaborative and vibrant startup culture. A team player with a sense of urgency will thrive in this role.
Role Overview and Responsibilities:
As a subject matter expert (SME), this position will be responsible for manufacturing science efforts supporting TScan’s internal and external technology transfers and manufacturing process. This role helps develop and implement manufacturing process improvements, provide technical advice during manufacturing, support manufacturing investigations and risk assessment, and mitigate process risks. This position will collaborate closely with the process development, analytical development, supply chain, project management and manufacturing teams to ensure process implementation to commercial manufacturing following project timeline and TScan’s goals.
The successful candidate will have experience in at-scale cell therapy process development, GMP cell therapy manufacturing, and be able to work highly independently in a fast-paced environment. Proven excellence in technical problem solving, project management, attention to detail, and communication is a must.
Responsibilities
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About TScan:
TScan Therapeutics was founded in 2018 by a small group of scientists led by Dr. Stephen Elledge (Harvard Medical School/HHMI). TScan is discovering and developing novel TCR-engineered T cell therapies for the treatment of cancer. TScan’s discovery platform is centered around a breakthrough technology that enables the rapid, comprehensive, and genome-wide identification of the peptide antigen targets of T cell receptors. This technology greatly enhances our ability to understand the specific antigens that drive important disease processes, including tumor cell recognition by the immune system, self-reactivity in autoimmune disorders, and acquired immunity in infectious disease. TScan is using the platform in oncology to discover new TCR/target pairs and to rapidly move novel TCRs into clinical development.
Do YOU have the anatomy of a TScanner?
Our talented, compassionate, and intelligent team is what makes TScan a great place to work. Our brand-new offices with approximately 40,000 square feet of premium lab, manufacturing and office space is an environment that supports innovation, camaraderie and professionalism. We are driven, passionate, fun, flexible and team oriented. Sound like you? Apply today.