Position Summary:

TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are looking for a Research Associate/Senior Research Associate in Cellular Analytical Development to join efforts in developing test methods for the company’s novel TCR-engineered T cell therapy products. This newly created role will reside within the Process and Analytical Sciences department and will report to the Associate Director of Cellular Analytical Development. Key activities will include the development and execution of analytical methods to support cellular process development and the tech transfer of in-process, release, and stability-indicating assay methods to QC, amongst others.

The ideal candidate will have essential knowledge in analytical method development and testing for cell and gene therapies including cell culture and nucleic acid analysis. Experiences with SOP documentation and statistical analysis are highly preferred. The ideal candidate will be self-motivated, capable of thriving in a fast-paced and agile environment, a team player with the ability to foster productive relationships with internal colleagues and external partners.

Responsibilities:

• Participate in the development, optimization, and qualification of analytical methods for TCR-engineered T cell processes and products.
• Work closely with Process Development team, perform timely in-process sample testing, generate reports to provide information for optimization.
• Contribute to tech transfer of optimized / qualified methods to QC and assist quality in developing testing strategies and validation efforts.
• Authorize and review technical documentation including SOPs, method development reports and meeting presentations.
• Maintain a detailed electronic laboratory notebook and present findings to the team, department, and company, as appropriate.

Requirements:

• Research Associate: BS with 0-3+ years of relevant experience
• Senior Research Associate: BS with 3-5+ years of relevant experience, or MS with 0-2 years of experience.
• Degree emphasis in immunology, cell biology, molecular biology, biochemistry, or related field is preferred.
• Experiences on mammalian cell culture and ddPCR are required; prior experiences with cell-based potency assays and method qualification are plus for consideration.
• Scientific creativity, critical thinking, ability to innovate, and analytical problem solving.
• Excellent communication skills (both written and oral) are critical.
• Experience drafting SOPs and testing documentation as well as supporting documentation for regulatory filings is strongly desired.

About TScan:

TScan Therapeutics is a fully integrated, next-generation TCR-T cell therapy company. Founded in 2018, TScan’s platform was developed by Stephen Elledge, Ph.D., and Tomasz Kula, Ph.D., at Brigham and Women’s Hospital and Harvard Medical School. TScan’s transformative platform enables rapid discovery of TCRs and targets for engineered T cell therapy. This technology is extremely versatile and is applicable across multiple therapeutic areas beyond cancers, including autoimmune disorders and infectious diseases.

Do YOU have the anatomy of a TScanner?

Our talented, compassionate, and intelligent team is what makes TScan a Top Place to Work (as ranked by The Boston Globe). Our state-of-the-art offices with over 70,000 square feet of premium lab space, including an internal GMP manufacturing suite, are an environment that supports innovation, camaraderie, and professionalism. We are passionate, fun, flexible, and team oriented. Sound like you? Apply today.

EEO Statement

TScan is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. TScan provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process and/or to perform the responsibilities of the position for which the applicant has applied, please contact the recruiter.

Recruitment & Staffing Agencies

TScan Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to TScan Therapeutics or its employees is strictly prohibited unless contacted directly by TScan Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of TScan Therapeutics, and TScan Therapeutics will not owe any referral or other fees with respect thereto.